製品の概要

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab4926 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • 備考


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human SCNN1B, catalog ab2906. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

関連情報

  • 別名
    • Amiloride sensitive sodium channel subunit beta
    • Amiloride-sensitive sodium channel subunit beta
    • Beta NaCH
    • Beta-ENaC
    • Beta-NaCH
    • ENaC beta
    • ENaCB
    • Epithelial Na(+) channel subunit beta
    • Epithelial Na+ channel beta subunit
    • Epithelial Na+ channel subunit beta
    • Epithelial sodium channel beta 2 subunit
    • Epithelial sodium channel beta 3 subunit
    • Nonvoltage gated sodium channel 1 beta subunit
    • Nonvoltage gated sodium channel 1 subunit beta
    • Nonvoltage-gated sodium channel 1 subunit beta
    • SCNEB
    • SCNN 1B
    • SCNN1B
    • SCNNB_HUMAN
    • Sodium channel nonvoltage gated 1 beta
    • Sodium channel nonvoltage gated 1 beta (Liddle syndrome)
    see all
  • 機能Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
  • 関連疾患Pseudohypoaldosteronism 1, autosomal recessive
    Liddle syndrome
    Bronchiectasis with or without elevated sweat chloride 1
  • 配列類似性Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1B subfamily.
  • 翻訳後修飾Phosphorylated on serine and threonine residues.
  • 細胞内局在Apical cell membrane. Apical membrane of epithelial cells.
  • Information by UniProt

SCNN1B peptide (ab4926) 使用論文

ab4926 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"