製品の概要

  • 製品名Anti-SCC112 antibody
    SCC112 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SCC112
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    antigen sequence: GRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQ DLAKKAAPAE RQIDLQ, corresponding to C terminal amino acids 1271-1336 of Human SCC112 (Isoform 1).

  • ポジティブ・コントロール
    • IHC-P: Human colon tissue WB: RT4 and U-251 MG cell lysates; Human plasma and tonsil lysates

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab122352 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/250 - 1/500.
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

ターゲット情報

  • 機能Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
  • 組織特異性Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney.
  • 配列類似性Belongs to the PDS5 family.
    Contains 1 HEAT repeat.
  • 発生段階Cell cycle-regulated with highest level in G2 phase.
  • 細胞内局在Nucleus. Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cell proliferation inducing protein 54 antibody
    • Cell proliferation-inducing gene 54 protein antibody
    • KIAA0648 antibody
    • PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) antibody
    • PDS5A antibody
    • PDS5A_HUMAN antibody
    • PIG54 antibody
    • SCC-112 antibody
    • SCC112 antibody
    • Sister chromatid cohesion protein 112 antibody
    • Sister chromatid cohesion protein PDS5 homolog A antibody
    see all

Anti-SCC112 antibody 画像

  • Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
    Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
  • All lanes : Anti-SCC112 antibody (ab122352) at 1/250 dilution

    Lane 1 : RT-4 cell line lysate
    Lane 2 : U-251 MG cell line lysate
    Lane 3 : Human plasma
    Lane 4 : Human liver tissue lysate
    Lane 5 : Human tonsil tissue lysate
  • ab122352, at 1/500, staining SCC112 in paraffin embedded Human colon tissue by Immunohistochemistry.
  • ab122352, at 4 µg/ml, staining SCC112 in U-251 MG cells by Immunofluorescence.

Anti-SCC112 antibody (ab122352) 使用論文

ab122352 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"