Anti-Scavenger Receptor BI + BII 抗体 (ab36970)


  • 製品名Anti-Scavenger Receptor BI + BII antibody
  • 製品の詳細
    Rabbit polyclonal to Scavenger Receptor BI + BII
  • 特異性ab36970 is specific for SR-BI and SR-BII.
  • アプリケーション適用あり: WB, ICC/IF, IP, Blockingmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide, corresponding to extracellular amino acids 230-280 of Scavenger Receptor BI + BII

  • ポジティブ・コントロール
    • Tissues that express SR-BI and/or SR-BII such as such as liver, ovary, adrenal glands, and to as lesser extent testes, heart and mammary glands.


Our Abpromise guarantee covers the use of ab36970 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 82 kDa.
ICC/IF 1/1000.
IP 1/100.
Blocking 1/100.


  • 関連性High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
  • 細胞内局在Lysosome; lysosomal membrane; multi-pass membrane protein.
  • 参照データベース
  • 別名
    • CD36 and LIMPII Analogous 1 antibody
    • CD36L1 antibody
    • CD36L2 antibody
    • CLA1 antibody
    • HLGP85 antibody
    • LGP85 antibody
    • LIMP II antibody
    • SCARB1 antibody
    • SCARB2 antibody
    • Scavenger receptor class B member 2 antibody
    • Scavenger Receptor Class B Type I antibody
    • SRBI antibody
    • SRBII antibody
    see all

Anti-Scavenger Receptor BI + BII antibody 画像

  • All lanes : Anti-Scavenger Receptor BI + BII antibody (ab36970) at 1/1000 dilution

    Lane 1 : wild-type mice
    Lane 2 : SR-BI deficient mice

    Predicted band size : 82 kDa
  • Anti-Scavenger Receptor BI + BII antibody (ab36970) at 1/1000 dilution + 80 µg of total mouse liver lysates

    Predicted band size : 82 kDa

Anti-Scavenger Receptor BI + BII antibody (ab36970) 使用論文

This product has been referenced in:
  • Badeau RM  et al. Human macrophage cholesterol efflux potential is enhanced by HDL-associated 17beta-estradiol fatty acyl esters. J Steroid Biochem Mol Biol 116:44-9 (2009). Blocking ; Human . Read more (PubMed: 19406243) »
  • Acín S  et al. Hydroxytyrosol administration enhances atherosclerotic lesion development in apo E deficient mice. J Biochem (Tokyo) 140:383-91 (2006). Read more (PubMed: 16873395) »

See all 2 Publications for this product

Product Wall

Thank you for taking the time to contact us. I am sorry to hear you have some concerns regarding this antibody.

In this case, I would suggest the white powder you are seeing may be precipitate. We recommend that aliquots of antibody should b...

Read More

Thank you for your reply and all the additional information. This makes the problems you have been experiencing much clearer to understand. It is clear that you have spent a lot of time in trying to optimise these antibodies and I am sorry that they ar...

Read More

Thank you for your reply.

I am very sorry that you have not been satisfied with the way we have handeled your complaints. I do understand and appreciate the amount of time you have spent it the laboratory. Our policy is that we are happy to o...

Read More

Thank you for reporting the problems encountered with these antibodies and for taking the time to complete the questionnaire. I am sorry to hear that these antibodieshave not providing satisfactory results so far.

The details provided will e...

Read More

Thank you for your enquiry

We obtain this product from an external source and unfortunately they are not able to provide specific information about the sample preparation.

I reviewed the literature and found the following protocol...

Read More