製品の概要

  • 製品名
    SC-66
  • 製品の詳細
    Allosteric Akt inhibitor
  • 生理活性の詳細
    Allosteric Akt inhibitor. Interferes with PIP3 binding to Akt's PH domain. Additionally facilitates Akt ubiquitination. Displays anticancer activity in vitro and in vivo.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Jo H  et al. Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination. Proc Natl Acad Sci U S A 108:6486-91 (2011). Read more (PubMed: 21464312) »

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