製品の概要

  • 製品名SC-560
  • 製品の詳細
    Highly selective COX-1 inhibitor
  • 生理活性の詳細Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 9 nM and 6.3 μM for COX-1 and COX-2, respectively). Displays anti-inflammatory, antitumor and antiviral activity. Orally active.
  • 精製度> 99%

製品の特性

    SC-560 (ab120649) 使用論文

    This product has been referenced in:
    • Okamoto M  et al. Anti-bovine viral diarrhoea virus and hepatitis C virus activity of the cyclooxygenase inhibitor SC-560. Antivir Chem Chemother 20:47-54 (2009). Read more (PubMed: 19794231) »
    • Choi SH  et al. Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury. FASEB J 22:1491-501 (2008). Read more (PubMed: 18162486) »
    • Brenneis C  et al. Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition. FASEB J 20:1352-60 (2006). Read more (PubMed: 16816110) »
    • Daikoku T  et al. Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. Cancer Res 65:3735-44 (2005). Read more (PubMed: 15867369) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"