製品の概要

  • 製品名SB431542
  • 製品の詳細
    ALK inhibitor
  • 生理活性の詳細Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC50 = 94 nM), and 7.
  • 精製度> 99%

製品の特性

    SB431542 (ab120163) 使用論文

    This product has been referenced in:
    • Halder SK  et al. A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers. Neoplasia 7:509-21 (2005). Read more (PubMed: 15967103) »
    • Laping NJ  et al. Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542. Mol Pharmacol 62:58-64 (2002). Read more (PubMed: 12065755) »
    • Inman GJ  et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol 62:65-74 (2002). Read more (PubMed: 12065756) »

    See all 6 Publications for this product

    Product Wall


    Q1. What is the molecular weight of SB431542?
    A1. The molecular weight of this molecule as measured by mass spec (as can be found under the Analysis section of the COA) is 385.2 daltons. The molecular weight to use for calculations by the use...

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    Information about the molecular weights can be found on the Biochemicals FAQ page.
    'Molecular weight and molecular formula
    The molecular weight and formula published on our website represent the molecular weight and formula of the product as ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"