製品の概要

  • 製品名SB 699551 dihydrochloride
  • 製品の詳細
    Selective 5-HT5A receptor antagonist
  • 別名
    • SB 699551-A
  • 生理活性の詳細Selective 5-HT5A receptor antagonist (pKi values are 8.3, for 5-HT5A and < 6.0 for 5-HT1B/D, 5-HT2A, 5-HT2C, 5-HT1A and 5-HT7 receptors). Increases extracellular 5-HT levels.
  • 精製度> 98%

製品の特性

    SB 699551 dihydrochloride (ab120590) 使用論文

    This product has been referenced in:
    • Thomas DR 5-ht5A receptors as a therapeutic target. Pharmacol Ther 111:707-14 (2006). Read more (PubMed: 16516972) »
    • Thomas DR  et al. SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain. Neuropharmacology 51:566-77 (2006). Read more (PubMed: 16846620) »
    • Corbett DF  et al. Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry. Bioorg Med Chem Lett 15:4014-8 (2005). Read more (PubMed: 16002289) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120590.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"