SB 334867, OX1 receptor antagonist (ab120164)
Key features and details
- Selective OX1 receptor antagonist
- CAS Number: 792173-99-0
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
SB 334867, OX1 receptor antagonist -
製品の詳細
Selective OX1 receptor antagonist -
生理活性の詳細
Selective OX1 receptor antagonist. Inhibits orexin-A induced intracellular calcium release (IC50 = 226 nM). Shows anxiolytic, sedative and anorectic effects in vivo.
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精製度
> 99% -
CAS 番号
792173-99-0 -
構造式
製品の特性
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体系名
N-(2-Methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-ylurea -
分子量
319.32 -
分子式
C17H13N5O2 -
PubChem 登録番号
6604926 -
保存方法
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120164 は 1 報の論文で使用されています。
- Huang L et al. Low-intensity focused ultrasound attenuates early traumatic brain injury by OX-A/NF-κB/NLRP3 signaling pathway. Aging (Albany NY) 14:7455-7469 (2022). PubMed: 36126193