Anti-Sarcomeric Alpha Actinin 抗体 (ab113086)

製品の概要

  • 製品名Anti-Sarcomeric Alpha Actinin antibody
    Sarcomeric Alpha Actinin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Sarcomeric Alpha Actinin
  • アプリケーション適用あり: WB, IHC-P, ICC, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Monkey, Zebrafish
  • 免疫原

    Recombinant Human Sarcomeric Alpha Actinin.

  • ポジティブ・コントロール
    • Human Heart and Skeletal Muscle tissues; A431 and H1299 whole cell lysates; HeLa cells.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113086 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 104 kDa.
IHC-P Use a concentration of 10 µg/ml.
ICC Use at an assay dependent concentration.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
  • 組織特異性Expressed in both skeletal and cardiac muscle.
  • 関連疾患Defects in ACTN2 are the cause of cardiomyopathy dilated type 1AA (CMD1AA) [MIM:612158]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • 配列類似性Belongs to the alpha-actinin family.
    Contains 1 actin-binding domain.
    Contains 2 CH (calponin-homology) domains.
    Contains 2 EF-hand domains.
    Contains 4 spectrin repeats.
  • 細胞内局在Cytoplasm > myofibril > sarcomere > Z line. Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Actin binding protein antibody
    • Actinin alpha 2 antibody
    • ACTN 2 antibody
    • ACTN2 antibody
    • ACTN2_HUMAN antibody
    • Alpha actinin 2 antibody
    • Alpha actinin skeletal muscle antibody
    • Alpha actinin skeletal muscle isoform 2 antibody
    • Alpha-actinin skeletal muscle isoform 2 antibody
    • Alpha-actinin-2 antibody
    • CMD1AA antibody
    • F actin cross linking protein antibody
    • F-actin cross-linking protein antibody
    see all

Anti-Sarcomeric Alpha Actinin antibody 画像

  • ab113086 at 10 µg/ml staining Sarcomeric Alpha Actinin in Formalin-fixed, Paraffin-embedded Human Heart tissue by Immunohistochemistry.
  • ab113086 at 10 µg/ml staining Sarcomeric Alpha Actinin in Formalin-fixed, Paraffin-embedded Human Skeletal muscle tissue by Immunohistochemistry.
  • All lanes : Anti-Sarcomeric Alpha Actinin antibody (ab113086) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 104 kDa
  • ab112086 at 1/200 dilution staining Sarcomeric Alpha Actinin in Paraformaldehyde-fixed HeLa cells by Immunofluorescence. The lower image is merged with DNA probe.

Anti-Sarcomeric Alpha Actinin antibody (ab113086) 使用論文

ab113086 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113086.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"