製品の概要

  • 製品名
    Anti-Sarcalumenin antibody [XIIC4]
    Sarcalumenin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [XIIC4] to Sarcalumenin
  • 特異性
    This antibody specifically detects sarcalumenin and the 53 kDa glycoprotein splice variant.
  • アプリケーション
    適用あり: ICC/IF, WB, Inhibition Assay, IP, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Rabbit, Guinea pig, Dog, Human
  • 免疫原

    Full length native protein (purified) corresponding to Rabbit Sarcalumenin. Purified from rabbit sarcoplasmic reticulum membrane vesicles.

  • ポジティブ・コントロール
    • Rabbit skeletal muscle extracts.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.05% Sodium azide
  • Concentration information loading...
  • 精製度
    Protein A purified
  • 一次抗体 備考
    Sarcalumenin is a 160 kDa acidic calcium binding glycoprotein found to reside at the inner membrane of the sarcoplasmic reticulum in a calcium dependent manner.The gene encoding sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein which co-localizes with sarcalumenin. These two proteins are found in the longitudinal sarcoplasmic reticulum and the nonjunctional membranes of the terminal cisternae. They have been observed to co-localize with calcium-ATPase suggesting that they are involved in calcium transport and sequestration.
  • ポリ/モノ
    モノクローナル
  • クローン名
    XIIC4
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab2874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/500.

Immunofluorescence staining of sarcalumenin and its splice variant in rabbit skeletal muscle results in staining that co-localizes with calcium ATPase in the longitudinal sarcoplasmic reticulum (SR) and the terminal cisternae.

WB 1/500.

By Western blot, this antibody detects a 53 kDa and a 160 kDa protein representing the glycoprotein and sarcalumenin, respectively, in rabbit skeletal muscle extracts.

Inhibition Assay Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
IHC-Fr 1/100.

ターゲット情報

参考文献

This product has been referenced in:
  • Kutchai H & Campbell KP Calcium transport by sarcoplasmic reticulum of skeletal muscle is inhibited by antibodies against the 53-kilodalton glycoprotein of the sarcoplasmic reticulum membrane. Biochemistry 28:4830-9 (1989). Read more (PubMed: 2527558) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab2874.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録