製品の概要

  • 製品名Anti-SAR1B antibody
    SAR1B 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to SAR1B
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide:

    DHERLLESKEELD

    , corresponding to internal sequence amino acids 104-116 of Human SAR1B (NP_001028675.1; NP_057187.1)

  • ポジティブ・コントロール
    • Mouse and Rat Liver lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報Peptide ELISA: antibody detection limit dilution: 1/8000.
    WB: Use at a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 22 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
    • 組織特異性Expressed in many tissues including small intestine, liver, muscle and brain.
    • 関連疾患Defects in SAR1B are the cause of chylomicron retention disease (CMRD) [MIM:246700]; also known as Anderson disease (ANDD). CMRD is an autosomal recessive disorder of severe fat malabsorption associated with failure to thrive in infancy. The condition is characterized by deficiency of fat-soluble vitamins, low blood cholesterol levels, and a selective absence of chylomicrons from blood. Affected individuals accumulate chylomicron-like particles in membrane-bound compartments of enterocytes, which contain large cytosolic lipid droplets.
    • 配列類似性Belongs to the small GTPase superfamily. SAR1 family.
    • 細胞内局在Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ANDD antibody
      • CMRD antibody
      • GTBPB antibody
      • GTP binding protein SAR1b antibody
      • GTP binding protein Sara antibody
      • GTP-binding protein B antibody
      • GTP-binding protein SAR1B antibody
      • SAR1 gene homolog B (S. cerevisiae) antibody
      • SAR1 homolog B antibody
      • SAR1a gene homolog 2 antibody
      • SAR1B antibody
      • SAR1B_HUMAN antibody
      • SARA2 antibody
      • SARB antibody
      see all

    Anti-SAR1B antibody 画像

    Anti-SAR1B antibody (ab77279) 使用論文

    ab77279 has not yet been referenced specifically in any publications.

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    Code de remise : *******
    Date d’expiration : JJ MM AAAA

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"