製品の概要

  • 製品名Anti-Saporin antibody (HRP)
    Saporin 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Saporin (HRP)
  • 標識HRP
  • 特異性ab42903 recognises saporin.
  • アプリケーション適用あり: IHC-Frmore details
  • 種交差性
    Reacts with Saponaria officinalis (Soapwort). Not yet tested in other species.
  • 免疫原

    Chemical/ Small Molecule corresponding to Saporin.

  • 特記事項

    The antibody was coupled to Horseradish Peroxidase (HRP) and dialysed against PBS.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab42903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/350 - 1/1000.

ターゲット情報

  • 関連性Saporin is obtained from the seeds of the Soapwort plant (Saponaria officinalis), a plant that grows wildly in Britain and other parts of Europe. Saporin is a plant enzyme with N-glycosidase activity that depurinates a specific nucleotide in the ribosomal RNA 28S, thus irreversibly blocking protein synthesis. It belongs to the well-characterized family of ribosome-inactivating proteins (RIPs). There are two types of RIPs: type I, which are much less cytotoxic due to the lack of the B chain and type II, which are distinguished from type I RIPs by the presence of the B chain and their ability to enter cells on their own. However, type I RIPs can still be internalized by fluid-phase endocytosis. In the case of saporin, it was reported that saporin first binds to the alpha 2 macroglobulin receptor on human cells and is then internalized to the cytosol. Upon internalization, the ribosomes are inactivated, resulting in cell death. Among all type I RIPs saporin SO6 is the most widely used because it is easily obtainable and very stable.
  • 別名
    • Saporin antibody

Anti-Saporin antibody (HRP) (ab42903) 使用論文

ab42903 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab42903.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"