Anti-Pan-SAPAP 抗体 (ab67224)
Key features and details
- Rabbit polyclonal to Pan-SAPAP
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-Pan-SAPAP antibody -
製品の詳細
Rabbit polyclonal to Pan-SAPAP -
由来種
Rabbit -
特異性
Please note that the immunogen that generated ab67224 shares some sequence with other SAPAP/DLGAP proteins, including SAPAP1, SAPAP2, and SAPAP4, and preliminary data suggests this antibody may not be specific for SAPAP3.
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アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide corresponding to Human Pan-SAPAP.
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ポジティブ・コントロール
- WB: Rat brain tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab67224の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa).
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa). |
ターゲット情報
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関連性
SAPAP3, (DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 286923 Rat
- SwissProt: P97838 Rat
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別名
- DLGAP3 antibody
- DAP3 antibody
- Discs, large (Drosophila) homolog associated protein 3 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab67224 は論文での使用が確認できていません。