Rabbit polyclonal to SAMSN1
KLH conjugated synthetic peptide corresponding to a region within internal sequence amino acids 262-291 of Human SAMSN1 (NP_071419.3).
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Preservative: 0.09% Sodium Azide
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Immunogen affinity purified
ab107438 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 42 kDa.
Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.
Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
Contains 1 SAM (sterile alpha motif) domain.
Contains 1 SH3 domain.
Nucleus. Cytoplasm. Cell projection > ruffle. Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles.
Information by UniProt
Hematopoietic adapter containing SH3 and sterile α motif (SAM) domains 1 antibody
Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1 antibody
has not yet been referenced specifically in any publications.
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