製品の概要

  • 製品名Anti-SAFB antibody
    SAFB 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SAFB
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rabbit, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within residues 875 and the C-terminus (residue 915) of human SAFB (NP_002958.2).

  • ポジティブ・コントロール
    • Human breast adenocarcinoma. Mouse squamous cell carcinoma.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500.
    Antigen exposure is recommended.
    Antigen exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. Can inhibit cell proliferation.
    • 組織特異性Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
    • 配列類似性Contains 1 RRM (RNA recognition motif) domain.
      Contains 1 SAP domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp779C1727 antibody
      • glutathione S transferase fusion protein antibody
      • HAP antibody
      • HET antibody
      • HSP27 ERE TATA binding protein antibody
      • HSP27 ERE-TATA-binding protein antibody
      • HSP27 estrogen response element-TATA box-binding protein antibody
      • SAF B antibody
      • SAF-B antibody
      • SAF-B1 antibody
      • SAFB 1 antibody
      • SAFB antibody
      • SAFB1 antibody
      • SAFB1_HUMAN antibody
      • Scaffold attachment factor B1 antibody
      see all

    Anti-SAFB antibody 画像

    • ab84378 at 1/250, staining human SAFB in a section of human breast adenocarcinoma by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
    • ab84378 at 1/250 dilution, staining SAFB in FFPE section of mouse squamous cell carcinoma, by immunohistochemistry (formalin/PFA-fixed parafin-embedded sections)

    Anti-SAFB antibody (ab84378) 使用論文

    ab84378 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab84378.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"