Anti-SAFB 抗体 [4i59] (ab18086)

製品の概要

  • 製品名Anti-SAFB antibody [4i59]
    SAFB 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4i59] to SAFB
  • 特異性Ab18086 recognizes HET/SAFB, Mr 130kDa; and a protein, Mr 34kDa.
  • アプリケーション適用あり: WB, IP, ICC, IHC-Pmore details
  • 種交差性
    交差種: Human
    非交差種: Mouse
  • 免疫原

    Synthetic peptide:

    CPEARDKEDGRKF

    , corresponding to amino acids 345 to 357 of SAFB.

  • エピトープThe immunizing sequence has 8/11 identical amino acids in mouse and human transcription factor tbx2 (T-box protein 2).
  • ポジティブ・コントロール
    • An independent laboratory has shown HET/SAFB to be immunoprecipitated from MCF-7 and HepG2 cell lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 30% Glycerol, 0.15M Sodium chloride, 0.1M Tris glycine. pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名4i59
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab18086 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 102 kDa.
IP Use at an assay dependent dilution.
ICC Use at an assay dependent dilution.
IHC-P Use at an assay dependent dilution.

ターゲット情報

  • 機能Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. Can inhibit cell proliferation.
  • 組織特異性Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
  • 配列類似性Contains 1 RRM (RNA recognition motif) domain.
    Contains 1 SAP domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp779C1727 antibody
    • glutathione S transferase fusion protein antibody
    • HAP antibody
    • HET antibody
    • HSP27 ERE TATA binding protein antibody
    • HSP27 ERE-TATA-binding protein antibody
    • HSP27 estrogen response element-TATA box-binding protein antibody
    • SAF B antibody
    • SAF-B antibody
    • SAF-B1 antibody
    • SAFB 1 antibody
    • SAFB antibody
    • SAFB1 antibody
    • SAFB1_HUMAN antibody
    • Scaffold attachment factor B1 antibody
    see all

Anti-SAFB antibody [4i59] (ab18086) 使用論文

ab18086 has not yet been referenced specifically in any publications.

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Thank you for your enquiry. I can tell you that the tissue tested in IHC was the human cell line MCF-7 human breast adenocarcinoma cell line and also the human hepatocellular liver carcinoma cell line HepG2. I have no information available on an ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"