Saclofen, GABAB antagonist (ab120327)
Key features and details
- GABAB antagonist
- CAS Number: 125464-42-8
- Soluble in water to 10 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
Saclofen, GABAB antagonist -
製品の詳細
GABAB antagonist -
生理活性の詳細
GABAB antagonist
Also available in simple stock solutions (ab146704) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS 番号
125464-42-8 -
構造式
製品の特性
-
体系名
3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid -
分子量
249.72 -
分子式
C9H12ClNO3S -
PubChem 登録番号
122150 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 10 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES 線形表記
Clc1ccc(cc1)C(CS(=O)(=O)O)CN -
由来
Synthetic
-
研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (4)
ab120327 は 4 報の論文で使用されています。
- Kosillo P et al. Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons. Cereb Cortex N/A:N/A (2016). PubMed: 27566978
- Platt NJ et al. Striatal dopamine transmission is subtly modified in human A53Ta-synuclein overexpressing mice. PLoS One 7:e36397 (2012). PubMed: 22570709
- Threlfell S et al. Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons. Neuron 75:58-64 (2012). PubMed: 22794260
- Hartung H et al. Nitric oxide donors enhance the frequency dependence of dopamine release in nucleus accumbens. Neuropsychopharmacology 36:1811-22 (2011). PubMed: 21508928