製品の概要

  • 製品名Ryanodine
  • 製品の詳細
    Ca2+ release modulator
  • 生理活性の詳細Alkaloid that binds with high affinity to ryanodine receptors to modulate intracellular Ca2+ release. Has complex actions and may stimulate or inhibit Ca2+ release, depending on the concentration used.
  • 精製度> 98%

製品の特性

    Ryanodine 画像

    • Ryanodine inhibits the elevation of intracellular Ca2+ by PI(3,5)P2 in primary cardiac myocytes. Top figure shows fura-2 ratiometric changes in intracellular Ca2+ in an isolated ventricular adult cardiac myocyte after treatment with PI(3,5)P2, ultimately resulting in contraction. Bottom figure shows that ryanodine inhibited the release of SR Ca2+ to both caffeine and PI(3,5)P2.

    Ryanodine (ab120083) 使用論文

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