Anti-RSUME 抗体 (ab91555)
Key features and details
- Rabbit polyclonal to RSUME
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-RSUME antibody -
製品の詳細
Rabbit polyclonal to RSUME -
由来種
Rabbit -
特異性
At least four isoforms of RSUME are known to exist; this antibody will only detect the largest isoform. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab91555の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 31 kDa.
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 31 kDa. |
ターゲット情報
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機能
Enhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination. -
組織特異性
Expressed in a wide number of tissues with highest expression in cerebellum, pituitary, heart, kidney, liver, stomach, pancreas, prostate and spleen. Low levels in thalamus, spinal cord, esophagus, thymus, lung and peripheral blood leukocytes. -
配列類似性
Contains 1 RWD domain. -
ドメイン
The RWD domain is required for the sumoylation enhancement activity. -
細胞内局在
Nucleus. Cytoplasm. Colocalizes with UBC9/UBE2I in nuclear spots. - Information by UniProt
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参照データベース
- Entrez Gene: 65026 Rat
- SwissProt: P0C7N0 Rat
- Unigene: 54470 Rat
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別名
- DKFZp566K023 antibody
- RSUME antibody
- RWD containing sumoylation enhancer antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab91555 は 1 報の論文で使用されています。
- Chen X et al. Knockdown of RWD domain containing 3 inhibits the malignant phenotypes of glioblastoma cells via inhibition of phosphoinositide 3-kinase/protein kinase B signaling. Exp Ther Med 16:384-393 (2018). PubMed: 29977365