製品の概要

  • 製品名
    Ruthenium red
  • 製品の詳細
    Ca2+ signaling inhibitor
  • 生理活性の詳細
    Ca2+ signaling inhibitor. Inhibits mitochondrial Ca2+ uniporter, Ca2+-ATPase, troponin C and calmodulin. Blocks intracellular Ca2+ release by ryanodine receptor from internal stores. Attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Blocks large-conductance Ca2+-activated potassium channels

製品の特性

参考文献

This product has been referenced in:
  • Israelson A  et al. Mapping the ruthenium red-binding site of the voltage-dependent anion channel-1. Cell Calcium 43:196-204 (2008). Read more (PubMed: 17590433) »
  • Cibulsky SM & Sather WA Block by ruthenium red of cloned neuronal voltage-gated calcium channels. J Pharmacol Exp Ther 289:1447-53 (1999). Read more (PubMed: 10336538) »
  • Tapia R & Velasco I Ruthenium red as a tool to study calcium channels, neuronal death and the function of neural pathways. Neurochem Int 30:137-47 (1997). Read more (PubMed: 9017661) »

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