製品の概要

  • 製品名Anti-RRM2 antibody
    RRM2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RRM2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 36-85 (ALSGTRVLAS KTARRIFQEP TEPKTKAAAP GVEDEPLLRE NPRRFVIFPI) of Human RRM2 (NP_001025).

  • ポジティブ・コントロール
    • Human fetal muscle lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab87227 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
  • パスウェイGenetic information processing; DNA replication.
  • 配列類似性Belongs to the ribonucleoside diphosphate reductase small chain family.
  • 翻訳後修飾Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • cb111 antibody
    • chunp6884 antibody
    • etID309896.20 antibody
    • R2 antibody
    • reductase M2 polypeptide variant 1 antibody
    • reductase M2 polypeptide variant 2 antibody
    • reductase M2 polypeptide variant 3a antibody
    • reductase M2 polypeptide variant 3b antibody
    • reductase M2 polypeptide variant 3c antibody
    • reductase M2 polypeptide variant 3d antibody
    • Ribonucleoside-diphosphate reductase subunit M2 antibody
    • Ribonucleotide reductase M2 antibody
    • Ribonucleotide reductase M2 polypeptide antibody
    • Ribonucleotide reductase M2 subunit antibody
    • ribonucleotide reductase protein r2 class I antibody
    • Ribonucleotide reductase regulatory subunit M2 antibody
    • Ribonucleotide reductase small chain antibody
    • Ribonucleotide reductase small subunit antibody
    • Ribonucleotide reductase, R2 subunit antibody
    • RIR2_HUMAN antibody
    • RR2 antibody
    • RR2M antibody
    • RRM2 antibody
    see all

Anti-RRM2 antibody 画像

  • Anti-RRM2 antibody (ab87227) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 45 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.

Anti-RRM2 antibody (ab87227) 使用論文

ab87227 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"