製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to RREB1
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 1375-1425 of Human RREB1 (NP_002946.4).

  • ポジティブ・コントロール
    • HeLa whole cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-10 µg/mg of lysate.
  • 追加情報
    Is unsuitable for WB.
  • ターゲット情報

    • 機能
      Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.
    • 組織特異性
      Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
    • 配列類似性
      Belongs to the krueppel C2H2-type zinc-finger protein family.
      Contains 15 C2H2-type zinc fingers.
    • 翻訳後修飾
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在
      Nucleus speckle.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FINB antibody
      • Finger protein in nuclear bodies antibody
      • Hindsight homolog antibody
      • HNT antibody
      • LZ321 antibody
      • Raf responsive zinc finger protein LZ321 antibody
      • Raf-responsive zinc finger protein LZ321 antibody
      • RAS responsive element binding protein 1 antibody
      • Ras-responsive element-binding protein 1 antibody
      • RREB 1 antibody
      • RREB-1 antibody
      • Rreb1 antibody
      • RREB1_HUMAN antibody
      • Zep 1 antibody
      • Zep-1 antibody
      • Zep1 antibody
      • Zinc finger motif enhancer binding protein 1 antibody
      • Zinc finger motif enhancer-binding protein 1 antibody
      see all

    画像

    • Detection of RREB1 in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab113287 at 6 µg/mg lysate for IP. A Rabbit anti-RREB1 antibody which recognizes a downstream epitope was used at 1 µg/ml for subsequent Western blot detection. Lane 2 represents control IgG IP. Detection: Chemiluminescence with an exposure time of 30 seconds.

    プロトコール

    参考文献

    ab113287 has not yet been referenced specifically in any publications.

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