製品の概要

  • 製品名
    Anti-RRAGC antibody [2938C3a]
    RRAGC 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2938C3a] to RRAGC
  • アプリケーション
    適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment comprising of 50-200 amino acids from near the N terminus of Human RRAGC (NM_022157).

  • ポジティブ・コントロール
    • Recombinant fragment of human RRAGC.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab76577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.2 - 2 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 44 kDa).
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Has guanine nucleotide-binding activity but weak intrinsic GTPase activity. Probably required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.
  • 配列類似性
    Belongs to the GTR/RAG GTP-binding protein family.
  • 細胞内局在
    Cytoplasm. Nucleus. Lysosome. Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AU041672 antibody
    • FLJ13311 antibody
    • GTPase interacting protein 2 antibody
    • GTPase-interacting protein 2 antibody
    • GTR2 antibody
    • MGC47404 antibody
    • OTTHUMP00000000548 antibody
    • Rag C antibody
    • Rag C protein antibody
    • RAGC antibody
    • Ras related GTP binding C antibody
    • Ras-related GTP-binding protein C antibody
    • RP23 29H22.4 antibody
    • RRAGC antibody
    • RRAGC_HUMAN antibody
    • TIB929 antibody
    • YGR163W antibody
    see all

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プロトコール

参考文献

ab76577 has not yet been referenced specifically in any publications.

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