Anti-ROR alpha + beta + gamma 抗体 [H3925] (ab41942)

製品の概要

  • 製品名
    Anti-ROR alpha + beta + gamma antibody [H3925]
  • 製品の詳細
    Mouse monoclonal [H3925] to ROR alpha + beta + gamma
  • 特異性
    This antibody specifically recognizes ROR alpha, beta
  • アプリケーション
    適用あり: WB, ELISA, IP, IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 136-236 of Human ROR alpha + beta + gamma

  • ポジティブ・コントロール
    • Rat kidney collecting tubule and rat cerebrum nerve cells.
  • 特記事項

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by July 2018 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab41942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa.
ELISA Use a concentration of 0.2 µg/ml.
IP Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 関連性
    ROR alpha, beta and gamma are members of the NR1 subfamily of nuclear hormone receptors. They can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. ROR alpha binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. ROR beta is required for normal postnatal development of rod and cone photoreceptor cells.
  • 細胞内局在
    Nuclear
  • 参照データベース
  • 別名
    • NR1F1 antibody
    • RAR-related orphan receptor alpha antibody
    • RAR-related orphan receptor beta antibody
    • RAR-related orphan receptor gamma antibody
    • ROR1 antibody
    • ROR2 antibody
    • ROR3 antibody
    • RORA antibody
    • RORB antibody
    • RORC antibody
    • RZRA antibody
    see all

画像

  • Ab41942 at 10 µg/ml staining rat cerebrum nerve cells.
  • Ab41942 at 10 µg/ml staining rat kidney collecting tubules.

参考文献

This product has been referenced in:
  • Ma A  et al. Anti-inflammatory effects of oxymatrine on rheumatoid arthritis in rats via regulating the imbalance between Treg and Th17 cells. Mol Med Rep 15:3615-3622 (2017). Read more (PubMed: 28440447) »

See 1 Publication for this product

レビューと Q&A

Thank you for your enquiry. I am sorry that we do not have any experimental data for these 3 (ab41941, ab13114, ab13116) products that show reactivity with RORgamma T. Human RORgamma T is not clearly mentioned in NCBI database of Entrez. I only...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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