製品の概要
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製品名Anti-ROMO1 antibody
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製品の詳細Rabbit polyclonal to ROMO1
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由来種Rabbit
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アプリケーション適用あり: ICC/IF, IHC-Pmore details
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種交差性交差種: Human
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免疫原
antigen sequence corresponding to C terminal amino acids 49-79 (GRELMGGIGK TMMQSGGTFG TFMAIGMGIR C) of Human ROMO1.
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ポジティブ･コントロール
- Human duodenum tissue.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab121379 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF | Use a concentration of 1 - 4 µg/ml. Recommend PFA Fixation and Triton X-100 treatment |
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| IHC-P | 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence.
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組織特異性Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line.
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配列類似性Belongs to the MGR2 family.
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発生段階Expression increases in senescent cells.
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細胞内局在Mitochondrion membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 140823 Human
- SwissProt: P60602 Human
- Unigene: 472564 Human
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別名
- bA353C18.2 antibody
- C20orf52 antibody
- Mitochondrial targeting GXXXG protein antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-ROMO1 antibody (ab121379)Immunofluorescent staining of Human cell line U-251MG shows positivity in nuclei but not nucleoli. Recommended concentration of ab121379 1-4 µg/ml. Cells treated with PFA/Triton X-100. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROMO1 antibody (ab121379)ab121379 at 1/250 dilution staining ROMO1 in paraffin-embedded Human duodenum by Immunohistochemistry.
参考文献
ab121379 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"