製品の概要

  • 製品名Anti-ROM1 antibody
    ROM1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ROM1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Cow, Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 216-265 (CCNPHSPRPC LQNRLSDSYA HPLFDPRQPN QNLWAQGCHE VLLEHLQDLA) of human ROM1 (NP_000318)

  • ポジティブ・コントロール
    • Transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab80507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/312500.

ターゲット情報

  • 機能May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.
  • 組織特異性Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.
  • 関連疾患Defects in ROM1 may cause retinitis pigmentosa (RP) [MIM:268000]; when associated with defects in PRPH2.
  • 配列類似性Belongs to the PRPH2/ROM1 family.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Retinal outer segment membrane protein 1 antibody
    • Rod outer segment membrane protein 1 antibody
    • ROM antibody
    • ROM1 antibody
    • ROM1_HUMAN antibody
    • ROSP1 antibody
    • RP7 antibody
    • Tetraspanin 23 antibody
    • Tetraspanin-23 antibody
    • Tspan 23 antibody
    • Tspan-23 antibody
    • TSPAN23 antibody
    see all

Anti-ROM1 antibody 画像

  • Anti-ROM1 antibody (ab80507) at 1/1 dilution + transfected 293T cell lysate at 10 µg with 5% skim milk / PBS buffer

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 37 kDa
    Observed band size : 47 kDa (why is the actual band size different from the predicted?)

Anti-ROM1 antibody (ab80507) 使用論文

This product has been referenced in:
  • Kevany BM  et al. Structural and functional analysis of the native peripherin-ROM1 complex isolated from photoreceptor cells. J Biol Chem 288:36272-84 (2013). WB ; Cow . Read more (PubMed: 24196967) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"