製品の概要

  • 製品名Anti-RNF40 antibody
    RNF40 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RNF40
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla
  • 免疫原

    Synthetic peptide corresponding to a region between residues 540 and 590 of human RNF40 (NP_055586.1)

  • ポジティブ・コントロール
    • Human mucinous ovarian carcinoma and human prostate adenocarcinoma tissues.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. Required for transcriptional activation of Hox genes.
    • 組織特異性Ubiquitously expressed. Expressed at higher level in testis, heart and pancreas, while it is only weakly expressed in lung, skeletal muscle and small intestine.
    • パスウェイProtein modification; protein ubiquitination.
    • 配列類似性Belongs to the BRE1 family.
      Contains 1 RING-type zinc finger.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 95 kDa retinoblastoma associated protein antibody
      • 95 kDa retinoblastoma protein binding protein antibody
      • 95 kDa retinoblastoma-associated protein antibody
      • BRE 1B antibody
      • BRE1 B antibody
      • BRE1 E3 ubiquitin ligase homolog B antibody
      • BRE1-B antibody
      • BRE1B antibody
      • BRE1B_HUMAN antibody
      • DKFZp686K191 antibody
      • E3 ubiquitin protein ligase BRE1B antibody
      • E3 ubiquitin-protein ligase BRE1B antibody
      • KIAA0661 antibody
      • MGC13051 antibody
      • Rb associated protein antibody
      • RBP 95 antibody
      • RBP95 antibody
      • RING finger protein 40 antibody
      • Ring finger protein 40 E3 ubiquitin protein ligase antibody
      • RNF 40 antibody
      • Rnf40 antibody
      • STARING antibody
      see all

    Anti-RNF40 antibody 画像

    • ab84515 at 1/250 dilution staining RNF40 in human mucinous ovarian carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
    • ab84515 at 1/250 dilution staining RNF40 in human prostate adenocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    Anti-RNF40 antibody (ab84515) 使用論文

    ab84515 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"