製品の概要

  • 製品名Anti-RNF111 antibody
    RNF111 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to RNF111
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Full length Human RNF111 (AAH60862.1).

  • ポジティブ・コントロール
    • Rat brain tissue lysate; RNF111 transfected 293T cell lysate; Human prostate tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab88535 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 109 kDa.
IHC-P Use a concentration of 3 µg/ml.

ターゲット情報

  • 機能Acts in the NODAL pathway of mesoderm patterning during embryonic development. Acts downstream AXIN1 as an E3 ubiquitin-protein ligase which promotes the ubiquitination of inhibitory SMADs such as SMAD7, induces their proteasomal degradation and thereby enhances the transcriptional activity of TGF-beta and BMP. Activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.
  • 組織特異性Broadly expressed.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Contains 1 RING-type zinc finger.
  • 細胞内局在Nucleus. Cytoplasm. Upon TGF-beta treatment, translocates from nucleus to cytosol.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARK antibody
    • Arkadia antibody
    • DKFZp313E0731 antibody
    • DKFZp686H1966 antibody
    • DKFZp761D081 antibody
    • E3 ubiquitin protein ligase Arkadia antibody
    • E3 ubiquitin-protein ligase Arkadia antibody
    • FLJ38008 antibody
    • RING finger protein 111 antibody
    • RN111_HUMAN antibody
    • RNF 111 antibody
    • RNF111 antibody
    see all

Anti-RNF111 antibody 画像

  • Anti-RNF111 antibody (ab88535) at 1 µg/ml + Rat brain lysate at 50 µg

    Predicted band size : 109 kDa
    Observed band size : 130 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-RNF111 antibody (ab88535) at 1 µg/ml

    Lane 1 : RNF111 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 109 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 125 kDa,230 kDa. We are unsure as to the identity of these extra bands.
  • ab88535, at 3µg/ml, staining RNF111 in formalin-fixed paraffin-embedded Human prostate tissue.

Anti-RNF111 antibody (ab88535) 使用論文

ab88535 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab88535.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"