製品の概要

  • 製品名
    Anti-RND3 antibody [4]
    RND3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4] to RND3
  • アプリケーション
    適用あり: WB, ICC/IF, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Purified recombinant full length RND3

  • ポジティブ・コントロール
    • HMVEC total cell extract.
  • 特記事項


    Monoclonal antibodies specific for RhoE(Rnd3) are an important tool for studying cell motility and cytoskeleton organization.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by July 2018 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab50316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 4 - 8 µg/ml. Predicted molecular weight: 27 kDa.
ICC/IF 1/200. PubMed: 19349584
IHC-Fr 1/200. PubMed: 19349584

ターゲット情報

  • 機能
    Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Belongs to the small GTPase superfamily. Rho family.
  • 細胞内局在
    Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARHE antibody
    • memB antibody
    • Protein MemB antibody
    • Ras homolog gene family member E antibody
    • Rho family GTPase 3 antibody
    • Rho-related GTP-binding protein Rho8 antibody
    • Rho-related GTP-binding protein RhoE antibody
    • Rho8 antibody
    • RhoE antibody
    • Rnd3 antibody
    • RND3_HUMAN antibody
    • Small GTP binding protein Rho8 antibody
    see all

参考文献

This product has been referenced in:
  • Pacary E  et al. Rnd3 coordinates early steps of cortical neurogenesis through actin-dependent and -independent mechanisms. Nat Commun 4:1635 (2013). IHC-Fr ; Mouse . Read more (PubMed: 23535656) »
  • Pacary E  et al. Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron 69:1069-84 (2011). ICC/IF ; Mouse . Read more (PubMed: 21435554) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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