製品の概要

  • 製品名Anti-RMI2 antibody
    RMI2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RMI2
  • アプリケーション適用あり: ICC/IF, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence: GKYVMVMGVV QACSPEPCLQ AVKMTDLSDN PIHESMWELE VEDLHRNI, corresponding to amino acids 99-146 of Human RMI2.

  • ポジティブ・コントロール
    • Human stomach tissue; RT 4, U 251 MG and Human liver lysates; U 251 MG cells.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab122685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 1 - 4 µg/ml. using PFA/Triton X-100 Fixation/Permeabilization.
WB 1/250 - 1/500.
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
  • 配列類似性Belongs to the RMI2 family.
    Contains 1 OB DNA-binding domain.
  • 翻訳後修飾Phosphorylated during mitosis.
  • 細胞内局在Nucleus. Colocalizes with BLM at nuclear DNA repair foci.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BLAP18 antibody
    • BLM-associated protein of 18 kDa antibody
    • C16orf75 antibody
    • hRMI2 antibody
    • MGC24665 antibody
    • RecQ-mediated genome instability protein 2 antibody
    • RMI2 antibody
    • RMI2_HUMAN antibody
    see all

Anti-RMI2 antibody 画像

  • ab122685, at 1/200 dilution, staining RMI2 in paraffin-embedded Human stomach tissue by Immunohistochemistry.
  • ab122685, at 4 µg/ml staining RIM2 in PFA/Triton X-100 fixed/permeabilized U 251 MG cells by Immunofluorescence (green).
  • All lanes : Anti-RMI2 antibody (ab122685) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

Anti-RMI2 antibody (ab122685) 使用論文

ab122685 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab122685.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"