Anti-RLTPR 抗体 (ab122717)
Key features and details
- Rabbit polyclonal to RLTPR
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-RLTPR antibody
RLTPR 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to RLTPR -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
antigen sequence: EVNELCQSVQ EHVELLGCGA GPQGEAAVRQ AEDAIQNANF SLSILPILYE AGSSPSHHWQ LGQKLEGLLR QVGEVCRQDI QDFTQ, corresponding to amino acids 729-813 of Human RLTPR.
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ポジティブ・コントロール
- Human rectum tissue
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特記事項
ab122717 is mono-specific.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
一次抗体 備考
ab122717 is mono-specific. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab122717の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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組織特異性
Expressed in all tissues tested, including thymus, spleen, colon, leukocytes, peripheral blood, skin, skin keratinocytes and skin fibroblasts. -
配列類似性
Belongs to the CARMIL family.
Contains 16 LRR (leucine-rich) repeats. -
発生段階
Expressed in fetal skin. - Information by UniProt
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参照データベース
- Entrez Gene: 146206 Human
- Omim: 610859 Human
- SwissProt: Q6F5E8 Human
- Unigene: 611432 Human
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別名
- CARMIL2 antibody
- CARMIL2b antibody
- Leucine rich repeat containing 16C antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab122717 は 5 報の論文で使用されています。
- Uchida Y et al. RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma. Eur J Haematol 106:221-229 (2021). PubMed: 33098696
- Shamriz O et al. Exogenous interleukin-2 can rescue in-vitro T cell activation and proliferation in patients with a novel capping protein regulator and myosin 1 linker 2 mutation. Clin Exp Immunol 200:215-227 (2020). PubMed: 32201938
- Alazami AM et al. Novel CARMIL2 Mutations in Patients with Variable Clinical Dermatitis, Infections, and Combined Immunodeficiency. Front Immunol 9:203 (2018). PubMed: 29479355
- Park J et al. Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood 130:1430-1440 (2017). PubMed: 28694326
- Schober T et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun 8:14209 (2017). WB ; Human . PubMed: 28112205