The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-RIC8 antibody (ab24383)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Protein Ric 8A
Protein Ric 8B
Resistance to inhibitors of cholinesterase 8 homolog A
Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
Resistance to inhibitors of cholinesterase 8 homolog B
Resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
RIC8 is a Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
The Caenorhabditis elegans protein Ric-8 has two mammalian homologs that have been identified : Ric-8A (Ric-8/synembryn) and Ric-8B. Synembryns are proteins that positively regulate synaptic transmission.
has not yet been referenced specifically in any publications.