Anti-RGS4 抗体 [2D3.3] (ab9962)

製品の概要

  • 製品名Anti-RGS4 antibody [2D3.3]
    RGS4 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [2D3.3] to RGS4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Purified recombinant 6X His-tagged full length human RGS4 protein.

  • エピトープN-terminus 22 aa.
  • 特記事項This antibody was raised in Armenian Hamster.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab9962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報Western blot: 1/500 block with 3% BSA, 1% non-fat dry milk in TBS-0.1% Tween (Whatman filtered).
  • ターゲット情報

    • 機能Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
    • 関連疾患Genetic variation in RGS4 is associated with susceptibility to schizophrenia type 9 (SCZD9) [MIM:604906]. A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder.
    • 配列類似性Contains 1 RGS domain.
    • 翻訳後修飾Palmitoylated on Cys-2 and/or Cys-12.
      Phosphorylated by cyclic GMP-dependent protein kinase.
    • Information by UniProt
    • 参照データベース
    • 別名
      • MGC2124 antibody
      • MGC60244 antibody
      • Regulator of G protein signalling 4 antibody
      • Regulator of G-protein signaling 4 antibody
      • RGP 4 antibody
      • RGP4 antibody
      • RGS 4 antibody
      • RGS4 antibody
      • RGS4_HUMAN antibody
      • Schizophrenia disorder 9 antibody
      • SCZD 9 antibody
      • SCZD9 antibody
      see all

    Anti-RGS4 antibody [2D3.3] (ab9962) 使用論文

    ab9962 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your patience, I have only just heard back from the antibody's originator. Ab9962 was raised in an Armenian hamster and will detect a band at 26 kDa. If you have any more questions, please contact us again.

    Thank you for your patience, I have only just heard back from the antibody's originator. Ab9962 was raised in an Armenian hamster. If you have any more questions, please contact us again.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"