製品の概要

  • 製品名Anti-RGS3 antibody
    RGS3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to RGS3
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-193 of Human RGS3

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
    • 配列類似性Contains 1 C2 domain.
      Contains 1 PDZ (DHR) domain.
      Contains 1 RGS domain.
    • 翻訳後修飾Phosphorylated by cyclic GMP-dependent protein kinase.
      ISGylated.
    • 細胞内局在Cytoplasm. Nucleus. Cell membrane. Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.
    • Information by UniProt
    • 参照データベース
    • 別名
      • C2PA antibody
      • FLJ20370 antibody
      • FLJ31516 antibody
      • FLJ90496 antibody
      • PDZ RGS 3 antibody
      • PDZ RGS3 antibody
      • Regulator of G protein signaling 3 antibody
      • Regulator of G protein signalling 3 antibody
      • Regulator of G-protein signaling 3 antibody
      • RGP 3 antibody
      • RGP3 antibody
      • RGS 3 antibody
      • RGS3 antibody
      • RGS3_HUMAN antibody
      see all

    Anti-RGS3 antibody 画像

    • RGS3 antibody (ab57923) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.
    • Western blot against tagged recombinant protein immunogen using ab57923 RGS3 antibody at 1ug/ml. Predicted band size of immunogen is 47 kDa

    Anti-RGS3 antibody (ab57923) 使用論文

    ab57923 has not yet been referenced specifically in any publications.

    Product Wall

    Application Western blot
    Sample Mouse Cell lysate - whole cell (MelJuSo)
    Loading amount 20 µg
    Specification MelJuSo
    Treatment Isoproterenol
    Gel Running Conditions Reduced Denaturing (10%)
    Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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    投稿 Nov 06 2012

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"