製品の概要

  • 製品名Anti-RGS2 antibody
    RGS2 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to RGS2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Amino acids 1-211 human RGS2

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 24 kDa.

ターゲット情報

  • 機能Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).
  • 組織特異性Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL).
  • 配列類似性Contains 1 RGS domain.
  • 翻訳後修飾Phosphorylated by protein kinase C. Phosphorylation by PRKG1 leads to activation of RGS2 activity.
  • 細胞内局在Cell membrane. Mitochondrion and Cell membrane. Cytoplasm. Nucleus, nucleolus.
  • Information by UniProt
  • 参照データベース
  • 別名
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    • OTTHUMP00000060765 antibody
    • Regulator of G protein signaling 2 antibody
    • Regulator of G protein signalling 2 24kD antibody
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    • RGS 2 antibody
    • RGS2 antibody
    • RGS2_HUMAN antibody
    see all

Anti-RGS2 antibody 画像



  • Predicted band size : 24 kDa


    Western blot analysis of E coli derived RGS2 fusion protein using ab14069 at 1/2000

Anti-RGS2 antibody (ab14069) 使用論文

ab14069 has not yet been referenced specifically in any publications.

Product Wall

I'm sorry to hear you are having problems with ab14069. I would like to recommend to block for 1 hr with 5% milk and to incubate the primary antibody overnight in TBST at 4C, then wash in TBST several times before applying the secondary antibody. ...

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Thank you for your enquiry. The WB test was done on a recombinant fusion protein. The size is much bigger than the native protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"