製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to RGR
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 76-125 (

    SLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRS

    ) of Human RGR, isoform 2 (NP_002912).

  • ポジティブ・コントロール
    • PANC-1 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性
    RGR is a putative retinal G-protein coupled receptor and is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. RGR acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal (the reverse isomerization occurs with rhodopsin in retinal photoreceptor cells). RGR is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
  • 細胞内局在
    Cell Membrane; Multi-pass membrane protein
  • 参照データベース
  • 別名
    • hRGR antibody
    • Ral GDS related protein antibody
    • Retinal G protein coupled receptor antibody
    • RGR-opsin antibody
    • RP44 antibody
    • RPE retinal G protein coupled receptor antibody
    see all

画像

  • Anti-RGR antibody (ab125371) at 1 µg/ml + PANC-1 cell lysate at 10 µg

    Predicted band size : 32 kDa

プロトコール

参考文献

ab125371 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab125371.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録