製品の概要

  • 製品名Anti-REXO1 antibody [4H5]
    REXO1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4H5] to REXO1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponding to amino acids 1060-1221 of Human REXO1 purified from E.coli.

  • ポジティブ・コントロール
    • 293T lysate
  • 特記事項


    ab66747, clone 4H5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human REXO1 protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 一次抗体 備考ab66747, clone 4H5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human REXO1 protein.
  • ポリ/モノモノクローナル
  • クローン名4H5
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab66747 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 132 kDa).
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation in vivo.
  • 細胞内局在Nuclear
  • 参照データベース
  • 別名
    • EloA BP1 antibody
    • ELOABP1 antibody
    • Elongin A binding protein 1 antibody
    • KIAA1138 antibody
    • REX1, RNA exonuclease 1 homolog (S. cerevisiae) antibody
    • RNA exonuclease 1 homolog antibody
    • TCEB3BP1 antibody
    • Transcription elongation factor B polypeptide 3 binding protein 1 antibody
    see all

Anti-REXO1 antibody [4H5] 画像

  • Anti-REXO1 antibody [4H5] (ab66747) at 1/1000 dilution + 293T cell lysate at 30 µg

    Secondary
    HRP-conjugated goat anti-mouse
    Developed using the ECL technique

    Predicted band size : 132 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-REXO1 antibody [4H5] (ab66747) 使用論文

ab66747 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"