Reversine, Cell-permeable A3 receptor antagonist (ab120921)
Key features and details
- Cell-permeable, selective A3 receptor antagonist. Potent MPS1 inhibitor.
- CAS Number: 656820-32-5
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Reversine, Cell-permeable A3 receptor antagonist -
製品の詳細
Cell-permeable, selective A3 receptor antagonist. Potent MPS1 inhibitor. -
精製度
> 98% -
CAS 番号
656820-32-5 -
構造式
製品の特性
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体系名
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine -
分子量
393.49 -
分子式
C21H27N7O -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 25 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1CCC(CC1)Nc1nc(Nc2ccc(cc2)N2CCOCC2)nc2[nH]cnc12 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab120921 は 3 報の論文で使用されています。
- Aldaz P et al. Identification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma. Cancers (Basel) 13:N/A (2021). PubMed: 33478100
- Xian S et al. The unfolded protein response links tumor aneuploidy to local immune dysregulation. EMBO Rep 22:e52509 (2021). PubMed: 34698427
- French BT & Straight AF CDK phosphorylation of Xenopus laevis M18BP1 promotes its metaphase centromere localization. EMBO J 38:N/A (2019). PubMed: 30606714