Anti-RXRG 抗体 (ab15518)
Key features and details
- Rabbit polyclonal to RXRG
- Suitable for: IHC-Fr, ICC/IF, IHC - Wholemount, WB, IHC-P
- Reacts with: Mouse, Rat, Chicken, Hamster, Human
- Isotype: IgG
製品の概要
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製品名
Anti-RXRG antibody
RXRG 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to RXRG -
由来種
Rabbit -
特異性
From Jan 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help.
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アプリケーション
適用あり: IHC-Fr, ICC/IF, IHC - Wholemount, WB, IHC-Pmore details -
種交差性
交差種: Mouse, Rat, Chicken, Hamster, Human -
免疫原
Synthetic peptide within Mouse RXRG aa 1-100 (N terminal). The exact sequence is proprietary.
Database link: P28705 -
特記事項
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab15518の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr | (1) |
Use at an assay dependent concentration.
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ICC/IF | (2) |
Use at an assay dependent concentration.
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IHC - Wholemount | (1) |
Use at an assay dependent concentration.
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WB | (2) |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa.
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IHC-P | (4) |
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC - Wholemount
Use at an assay dependent concentration. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa. |
IHC-P
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
ターゲット情報
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機能
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. -
配列類似性
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
ドメイン
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 396231 Chicken
- Entrez Gene: 6258 Human
- Entrez Gene: 20183 Mouse
- Entrez Gene: 83574 Rat
- Omim: 180247 Human
- SwissProt: P28701 Chicken
- SwissProt: P48443 Human
- SwissProt: P28705 Mouse
see all -
別名
- MGC109416 antibody
- NR2B3 antibody
- Nuclear receptor subfamily 2 group B member 3 antibody
see all
画像
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Anti-RXRG antibody (ab15518) at 1/25 dilution + NIH3T3 cell lysate
Predicted band size: 51 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted? -
ab15518 staining RXRG in breast carcinoma by Immunohistochemistry (FFPE-sections).
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (15)
ab15518 は 15 報の論文で使用されています。
- Gao K et al. Qishen granules exerts cardioprotective effects on rats with heart failure via regulating fatty acid and glucose metabolism. Chin Med 15:21 (2020). PubMed: 32158496
- Thulasi Raman SN et al. Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus. Emerg Microbes Infect 9:2046-2060 (2020). PubMed: 32873194
- Wang GS et al. Expression and localization of retinoid receptors in the testis of normal and infertile men. Mol Reprod Dev 87:978-985 (2020). PubMed: 32770619
- Joseph C et al. Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer. Br J Cancer 121:776-785 (2019). PubMed: 31558802
- Aldunate EZ et al. Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision. Sci Rep 9:2314 (2019). PubMed: 30783126