製品の概要
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製品名Retinal S antigen peptide
製品の詳細
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由来Synthetic
関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab4974 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking
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製品の状態Liquid
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備考
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat S-arrestin, catalog ab3435. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
関連情報
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別名
- 48 kDa protein
- Arrestin
- Arrestin 1
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機能Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
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組織特異性Retina and pineal gland.
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関連疾患Defects in SAG are a cause of congenital stationary night blindness Oguchi type 1 (CSNBO1) [MIM:258100]; also known as Oguchi disease. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. CSNBO is an autosomal recessive form associated with fundus discoloration and abnormally slow dark adaptation.
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配列類似性Belongs to the arrestin family.
- Information by UniProt
Retinal S antigen peptide (ab4974) 使用論文
ab4974 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"