Anti-Respiratory Syncytial Virus G Glycoprotein 抗体 [RSV133] (ab94966)

製品の概要

  • 製品名Anti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133]
  • 製品の詳細
    Mouse monoclonal [RSV133] to Respiratory Syncytial Virus G Glycoprotein
  • アプリケーション適用あり: ELISA, WB, ICC/IF, IHC-Frmore details
  • 種交差性
    交差種: Other
  • 免疫原

    Human Respiratory Syncytial Virus strain A2 infected HeLa cells

  • 特記事項Fusion partner: PS-NS/1-Ag4


    ab94966 is useful for the identification and location of expression of the G glycoprotein of Human Respiratory Syncytial Virus (HRSV) of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • 一次抗体 備考ab94966 is useful for the identification and location of expression of the G glycoprotein of Human Respiratory Syncytial Virus (HRSV) of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.
  • ポリ/モノモノクローナル
  • クローン名RSV133
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab94966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.
ICC/IF Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration. Fix with Acetone.

ターゲット情報

  • 関連性Respiratory Syncytial Virus (RSV) G Glycoprotein attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. It interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, it lacks both neuraminidase and hemagglutinating activities.
  • 細胞内局在Virion membrane. Host cell surface
  • 別名
    • Attachment glycoprotein G antibody
    • G antibody
    • Major surface glycoprotein G antibody
    • Membrane bound glycoprotein antibody
    • mG antibody
    • RSV G Glycoprotein antibody
    see all

Anti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133] (ab94966) 使用論文

This product has been referenced in:
  • Le Nouën C  et al. Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization. Proc Natl Acad Sci U S A 111:13169-74 (2014). Read more (PubMed: 25157129) »

See 1 Publication for this product

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I was trying to find the source of the statement: "This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infec...

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We used Human RSV strain A2 infected HeLa cells to raise this antibody. The exact epitope sequence has not been determined so I am sorry we do not have, any extra information, other than what is already on the datashee...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"