Anti-Respiratory Syncytial Virus 抗体 [8B10] (ab10016)

製品の概要

  • 製品名Anti-Respiratory Syncytial Virus antibody [8B10]
    Respiratory Syncytial Virus 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [8B10] to Respiratory Syncytial Virus
  • 特異性Nucleoprotein (N) protein specific. Reacts only with mature virions with completely assembled nucleocapsids. Fails to reorganize the N-protein epitope of immature and destroyed virions, which indicates conformation dependence of the 8B10 binding site. No cross-reactivity with influenza A and B viruses, adenovirus and parainfluenza type 1 and 2 viruses.
  • アプリケーション適用あり: ICC/IF, ELISAmore details
  • 免疫原

    Full length native protein (purified RSV virus, strain Long).

  • 特記事項Concentration varies from lot to lot and can be provided on request.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)This antibody has been affinity purified. Purity tested by elcetrophoresis.
  • ポリ/モノモノクローナル
  • クローン名8B10
  • ミエローマSp2/0
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab10016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
  • 細胞内局在Virion. Host cytoplasm
  • 別名
    • RS virus antibody
    • RSV antibody

Anti-Respiratory Syncytial Virus antibody [8B10] 画像

  • ab10016 staining Respiratory Syncytial Virus in apo E-deficient Mouse atherosclerotic plaque tissue by ICC/IF (Immunocytochemistry/immunofluorescence). Positive immunofluorescence for Respiratory Syncytial Virus is seen along the endothelial lining.

Anti-Respiratory Syncytial Virus antibody [8B10] (ab10016) 使用論文

This product has been referenced in:
  • Haidari M  et al. Influenza virus directly infects, inflames, and resides in the arteries of atherosclerotic and normal mice. Atherosclerosis 208:90-6 (2010). Read more (PubMed: 19665123) »
  • Marchant D  et al. Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism. J Virol 84:11359-73 (2010). Read more (PubMed: 20702616) »

See all 2 Publications for this product

Product Wall

Thank you for your inquiry. I have confirmed with the laboratory that we have tested this antibody with strain Long and unfortunately I do not have any information about reactivity with other strains. I hope this information is helpful. Please d...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"