製品の概要

  • 製品名Anti-RERE antibody
    RERE 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RERE
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Saccharomyces cerevisiae, Drosophila melanogaster
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 1-50 (TADKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNY A) of Human RERE, NP_036234

  • ポジティブ・コントロール
    • 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 172 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
  • 組織特異性Widely expressed. Expressed in tumor cell lines.
  • 関連疾患Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24).
  • 配列類似性Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.
  • ドメインThe interaction with ATN1 is mediated by the coiled coil domain.
  • 細胞内局在Nucleus. Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
  • Information by UniProt
  • 参照データベース
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    • Atrophin 1 related protein antibody
    • atrophin 2 antibody
    • atrophin related protein antibody
    • ATROPHIN-1-ASSOCIATED PROTEIN antibody
    • Atrophin-1-like protein antibody
    • Atrophin-1-related protein antibody
    • atrophin-2 antibody
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Anti-RERE antibody 画像

  • Anti-RERE antibody (ab86231) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 172 kDa

Anti-RERE antibody (ab86231) 使用論文

ab86231 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"