製品の概要

  • 製品名Anti-RERE antibody
    RERE 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RERE
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region within amino acids 389-418 from the N terminal region of Human RERE.

  • ポジティブ・コントロール
    • Neuro-2a cell line lysates; lung carcinoma tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 172 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
  • 組織特異性Widely expressed. Expressed in tumor cell lines.
  • 関連疾患Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24).
  • 配列類似性Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.
  • ドメインThe interaction with ATN1 is mediated by the coiled coil domain.
  • 細胞内局在Nucleus. Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
  • Information by UniProt
  • 参照データベース
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Anti-RERE antibody 画像

  • Anti-RERE antibody (ab103462) at 1/100 dilution + Neuro 2a cell line lysate at 35 µg

    Predicted band size : 172 kDa
  • ab103462, at a 1/50 dilution, staining RERE in formalin fixed and paraffin embedded lung carcinoma tissue by Immunohistochemistry. Developed using peroxidase conjugated secondary antibody and DAB staining.

Anti-RERE antibody (ab103462) 使用論文

ab103462 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (brain)
Specification brain
Fixative Paraformaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Tris-EDTA-Buffer pH 9,0
Permeabilization Yes - Wash-Buffer from DAKO with Tween
Username

Mr. Rudolf Jung

Verified customer

投稿 Feb 15 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"