製品の概要

  • 製品名Anti-Red Blood Cells antibody [34-3C]
    Red Blood Cells 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [34-3C] to Red Blood Cells
  • 特異性Recognizes an exposed surface determinant of intact Red Blood Cells. ab106101 only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC.
  • アプリケーション適用あり: Functional Studies, Flow Cytmore details
  • 種交差性
    交差種: Mouse
    非交差種: Rat, Sheep, Rabbit, Chicken, Human
  • 免疫原

    Mouse Red Blood Cells

  • ポジティブ・コントロール
    • Mouse erythrocytes
  • 特記事項


    This antibody efficiently binds to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)0.2 µm filtered solution
  • 一次抗体 備考This antibody efficiently binds to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity.
  • ポリ/モノモノクローナル
  • クローン名34-3C
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 関連性Red blood cells are the most common type of blood cell and are the vertebrate body's principal means of delivering oxygen from the lungs or gills to body tissues via the blood.
  • 別名
    • Erythrocytes antibody
    • RBCs antibody

Anti-Red Blood Cells antibody [34-3C] (ab106101) 使用論文

This product has been referenced in:
  • Baudino L  et al. Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. J Immunol 180:1948-53 (2008). Read more (PubMed: 18209093) »
  • Azeredo da Silveira S  et al. Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high affinity anti-erythrocyte autoantibody. J Exp Med 195:665-72 (2002). Read more (PubMed: 11901193) »

See all 3 Publications for this product

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There are currently no Abreviews or Questions for ab106101.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"