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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Typical enzyme concentration to support conjugation in vitro is 50-200 nM depending on conditions.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 50mM HEPES, 150mM Sodium chloride, pH 8.0
Anthracycline associated resistance ARX
Anthracycline-associated resistance ARX
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Protein modification; protein sumoylation.
Belongs to the ubiquitin-activating E1 family.
Information by UniProt
S. cerevisiae SAE2 / UBA2 protein (ab80727) 使用論文
has not yet been referenced specifically in any publications.
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