製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Rat

特性

Our Abpromise guarantee covers the use of ab93917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol

関連情報

  • 別名
    • 70 kDa lamin
    • CDCD1
    • CDDC
    • CMD1A
    • CMT2B1
    • EMD2
    • FPL
    • FPLD
    • HGPS
    • IDC
    • LA delta 50
    • Lamin A delta 50
    • LDP1
    • LFP
    • LGMD1B
    • LMN1
    • LMNA
    • LMNC
    • PRO1
    • renal carcinoma antigen NYREN32
    see all
  • 関連性
    Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin A and C. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acids internal deletion within the carboxyl-terminal domain of the protein. Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of LMNA gene.
  • 細胞内局在
    Cell Membrane, Cytoplasmic, intermediate filament and Nuclear

画像

  • ab93917 by SDS-PAGE (8% polyacrylamide) and stained with Coomassie Blue.
    Lane 1: MWM
    Lane 2: 4µg ab93917
    Lane 3: 3µg ab93917
    Lane 4: 2µg ab93917
    Lane 5: 1µg ab93917

参考文献

ab93917 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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