Recombinant rat IL17A + IL17F protein (ab109681)

製品の概要

  • 製品名
    Recombinant rat IL17A + IL17F protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列 1
    • アクセッション番号
    • 生物種
      Rat
    • 配列
      MAVLIPQSSVCPNAEANNFLQNVKVNLKVLNSLSSKASSRRPSDYLNRST SPWTLSRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILV LKREPEKCPFTFRVEKMLVGVGCTCVSSIVRHAS
    • 分子量
      15 kDa
    • 領域
      18 to 150
    アミノ酸配列 2
    • アクセッション番号
    • 生物種
      Rat
    • 配列
      MAVLIPQSSVCPNAEANNFLQNVKVNLKVLNSLSSKASSRRPSDYLNRST SPWTLSRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILV LKREPEKCPFTFRVEKMLVGVGCTCVSSIVRHAS
    • 分子量
      15 kDa
    • 領域
      29 to 161

特性

Our Abpromise guarantee covers the use of ab109681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    The ED50 of ab109681, as determined by its ability to induce IL-6 production in NIH-3T3 cells, is 7.28ng/mL.
  • アプリケーション

    HPLC

    SDS-PAGE

    Functional Studies

  • エンドトキシン・レベル
    < 0.100 Eu/µg
  • 精製度
    > 98 % SDS-PAGE.
    Purity Greater than 98% determined by reducing and non-reducing SDS-PAGE.
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

    Preservative: None

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions. The formulation is from 0.02% TFA before product is lyophilized

関連情報

  • 別名
    • Ctla 8
    • CTLA8
    • Cytokine ML1
    • Cytotoxic T lymphocyte associated antigen 8
    • CYTOTOXIC T LYMPHOCYTE ASSOCIATED SERINE ESTERASE 8
    • IL 17F
    • IL17
    • IL24
    • Interleukin 17A
    • Interleukin 17F
    • Interleukin 24
    • ML 1
    • ML1
    • mutant IL 17F
    see all
  • 関連性
    IL17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. IL17A induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.
  • 細胞内局在
    Secreted

画像

  • ab109681 used in Western Blot. Figure: 1 ug in each lane (-) non-reducing conditions and (+) reducing conditions in a 4-20% Tris-Glycine gel stained with Coomassie Blue. Rat IL-17AF is a heterodimer with a predicted total MW of 30.7 kDa.

参考文献

ab109681 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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