Recombinant rat FNTA + FNTB protein (ab90512)

製品の概要

  • 製品名
    Recombinant rat FNTA + FNTB protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Rat
    • タグ
      GST tag N-Terminus

関連製品

特性

Our Abpromise guarantee covers the use of ab90512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Activity: 1 pmol of FNTA + FNTB will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 5mM DTT, 100mM Sodium chloride, 100mM HEPES, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • 2010013E13Rik
    • AA409500
    • CAAX box, alpha
    • CAAX farnesyltransferase subunit alpha
    • CAAX farnesyltransferase subunit beta
    • Farnesyltransferase
    • Farnesyltransferase, CAAX box, beta
    • Farnesyltransferase, subunit alpha
    • FNTB
    • FPTA
    • FPTB
    • FTA
    • FTase beta
    • FTase-alpha
    • GGTase-I-alpha
    • MGC105303
    • MGC31935
    • MGC99680
    • PFAS
    • PGGT1A
    • Protein farnesyltransferase subunit beta
    • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
    • PTAR2
    • RAS proteins prenyltransferase beta
    • Ras proteins prenyltransferase subunit alpha
    • type I protein geranyl-geranyltransferase subunit alpha
    see all
  • 関連性
    FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTB, farnesyltransferase subunit beta, catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.

参考文献

ab90512 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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