製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus

特性

Our Abpromise guarantee covers the use of ab27714 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

  • 製品の状態Liquid
  • 備考Not enzymatically active. The protein is suspended in SDS/mercaptoethanol sample buffer with a bromphenol blue dye marker.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Constituents: 0.02% Bromophenol blue, 5% Beta mercaptoethanol, 2% SDS

関連情報

  • 別名
    • CVID9
    • D14Ertd420e
    • Kinase PKC delta
    • KPCD
    • KPCD_HUMAN
    • MAY 1
    • MAY1
    • MGC49908
    • nPKC delta
    • nPKC-delta
    • PCKd
    • PKC d
    • PKC delta
    • PKCD
    • PKCdelta
    • PRKC D
    • PRKC delta
    • Prkcd
    • Protein Kinase C delta
    • Protein kinase C delta type
    • Protein kinase C delta VIII
    • Protein Kinase Cdelta
    • Tyrosine protein kinase PRKCD
    see all
  • 機能This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
  • 配列類似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 C2 domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • ドメインThe C1 domain, containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B), is the diacylglycerol sensor.
    The C2 domain is a non-calcium binding domain. It binds proteins containing phosphotyrosine in a sequence-specific manner.
  • 翻訳後修飾Phosphorylated on Thr-507, within the activation loop. Autophosphorylated and/or phosphorylated. Although the Thr-507 phosphorylation occurs it is not a prerequisite for enzymatic activity.
  • 細胞内局在Cytoplasm. Membrane.
  • Information by UniProt

Recombinant PKC delta protein (ab27714) 使用論文

ab27714 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"